Mastered Tutorials

(Solved) N512 Module 1 Assignment

(Solved) N512 Module 1 Assignment

(Solved) N512 Advanced Pathophysiology- Sentinel U Simulations

N512 Module 1 Assignment

Cellular Function and Immunity

Case Studies Instructions

This week, you have two separate focus areas: Cellular Function and Immunity.

Some cases have multiple parts. Please read instructions carefully.

  • Use at least one in-text citations/references and include scholarly references (within the past 5 years). This can include your textbook.
  • Use literature supporting United States Clinical Practice Guidelines when available (go to PubMed, search “clinical guidelines” and “diagnosis you are researching”.

These case studies will help build your clinical intelligence. Thus, it is imperative use your own words. Do not use other student’s work or plagiarize from any source, including Artificial Intelligence. Paraphrase instead of including direct quotes.

Any use of Artificial Intelligence must be disclosed and cited using APA format. The purpose of this assignment is to help you learn for clinical practice, not to copy and paste. Please use this time for active learning.

  • Download this document, type your answers, include references (including at least one reference/in-text citations). Then turn into the appropriate assignment folder in your Moodle assignment folder (scroll to the bottom of the course).

Do not share your work with others (current or future students). Do not share these studies in any format for public or private use.

Turn-it-in is not required, as this is a template and repeats.

Cellular Function

 

Note: All case studies are provided as a learning tool for students who wish to have them. 

 

Part 1 – You are only required to answer one scenario of your choosing. You only have to choose the letter. 

Case 1: A 69-year-old female has a cystoscopy/biopsy report: Transitional cell carcinoma of the bladder.

 

Choose the tissue level the disease is affecting:

  1. Epithelial.
  2. Muscle.
  3. Connective.
  4. Neural.

 

Case 2: A 44-year-old female has a cervical cytology report: Atypical squamous cells of unknown significance.

 

Choose the tissue level the findings refer to:

  1. Connective.
  2. Neural.
  3. Muscle.
  4. Epithelial.

 

Case 3: A 49-year-old female wishes to receive injection fillers for her “smile and laugh lines.”

 

Choose the tissue level the injections are administered in:

  1. Connective.
  2. Epithelial.
  3. Neural.
  4. Muscle.

 

Case 4: A 47-year-old male is newly diagnosed with glioblastoma.

Choose the tissue level the disease is affecting:

  1. Neural.
  2. Epithelial.
  3. Muscle.
  4. Connective.

This is optional for all scenarios: Compare and contrast the types of tissue in the chart below:

 

Epithelial Connective Muscle Neural

 

Add your Reference:

 

[Reference in APA format]

Part 2 – You are only required to answer one case of your choosing. 

Case 1: Review and interpret (i.e., explain) the endometrial biopsy reports:

  1. Report A: Atrophic endometrium.
  2. Report B: Atypical adenomatous hyperplasia.

Case 2: Two clients have persistent gastroesophageal reflux disease (GERD) despite therapy.  Review and interpret their biopsy reports:

  1. Report A: Low-grade dysplasia.
  2. Report B: Intestinal metaplasia.

Add your Reference:

[Reference in APA format]

 

Part 3 – You are only required to answer one case of your choosing.

 

Case 1: A couple wishes to birth a second child. They have a 7-year-old with Down syndrome.

  1. Explain the general risk of Down syndrome and the recurrence risk in a second pregnancy.

Case 2: A 4-year-old male was just diagnosed with red/green color blindness.

  1. Discuss how red/green color blindness is inherited.
  2. Explain why only males are impacted.

 

Case 3: Fill in the Punnett squares for each. Discuss risks for subsequent births.

 

Cystic Fibrosis – both are carriers

 

Carrier Parent Carrier Parent

 

Marfan syndrome – one parent is affected and one is unaffected

 

Affected Parent Heterozygous Normal Parent Homozygous

 

Add your Reference:

 

[Reference in APA format]

 Immunity

Directions:

Please complete either case 1 or case 2 (your choosing) from Part 1.

Then, complete either case 1 or case 2 (your choosing) from Part 2.

Note: All case studies are provided as a learning tool for students who wish to have them.

Part 1– You are only required to answer one case of your choosing.

Case 1: A 23-year-old female is scared she may have genital herpes due to unprotected sex. She does not have any visible lesions and is requesting tests.

An antibody test is completed:

HSV 1 IgG type-specific antibody: < 0.90 (note: this is negative)

HSV 2 IgG type-specific antibody: > 1.10 (note: this is positive)

  1. How would you explain these results ?
  2. Can the provider tell if this is a recent or past infection?
  3. Can the provider tell how long ago she was infected?

 

Case 2: A client has possible anaphylaxis. An epinephrine intramuscular (IM) injection is given.

  1. Describe the therapeutic actions of epinephrine as they apply to immune alterations in anaphylaxis.

Add your Reference:

 

[Reference in APA format]

Part 2– You are only required to answer one case of your choosing.

 

Case 1: A 45-year-old male is concerned that he has HIV, as he had unprotected sex with an adult male.

Answer the following questions:

  1. Which HIV test should be conducted first?
  2. If the client had contracted HIV, how many days after exposure would be needed before the test would be positive?
  3. Would you consider offering him PEP or PrEP? If so, why and when?

Case 2: A 20-year-old female complains of unintentional weight loss and fatigue x 1 month. She claims her knees and wrist are “achy and stiff in the mornings”. The client has a rash around both cheek areas. She denies any past medical or surgical history. She denies medication use.

Physical exam: rash and edematous joints with pain upon range of motion.

The tentative diagnosis is systemic lupus erythematosus (SLE).

Answer the following questions:

  1. Which diagnostic lab tests evaluate for SLE?
  2. Which diagnostic lab test findings would correlate with SLE?
  3. What clinical manifestations support this diagnosis?

Add your Reference:

[Reference in APA format]

Please note that the source for the interactive activity content is the text, Applied Pathophysiology for the Advanced Practice Nurse, 2nd Edition by Dlugasch and Story (2024).

SOLUTION

 

Cellular Function

 

Note: All case studies are provided as a learning tool for students who wish to have them.

 

Part 1 – You are only required to answer one scenario of your choosing. You only have to choose the letter.

 

Case 1: A 69-year-old female has a cystoscopy/biopsy report: Transitional cell carcinoma of the bladder.

 

Choose the tissue level the disease is affecting:

  1. Epithelial. Transitional cell carcinoma originates from the epithelial lining of the bladder (Sanei‐Far & Gharib, 2024). The urothelium of the bladder is a specialized tissue of the epithelium with the ability to contract and stretch. Malignant changes in this layer result in bladder cancer.
  2. Muscle.
  3. Connective.
  4. Neural.

 

Case 2: A 44-year-old female has a cervical cytology report: Atypical squamous cells of unknown significance.

 

Choose the tissue level the findings refer to:

  1. Connective.
  2. Neural.
  3. Muscle.
  4. Epithelial.

 

Case 3: A 49-year-old female wishes to receive injection fillers for her “smile and laugh lines.”

 

Choose the tissue level the injections are administered in:

  1. Connective.
  2. Epithelial.
  3. Neural.
  4. Muscle.

 

Case 4: A 47-year-old male is newly diagnosed with glioblastoma.

 

Choose the tissue level the disease is affecting:

  1. Neural.
  2. Epithelial.
  3. Muscle.
  4. Connective.

 

 

This is optional for all scenarios: Compare and contrast the types of tissue in the chart below:

 

Epithelial Connective Muscle Neural

 

Add your Reference:

 

Sanei‐Far, Z., & Gharib, M. (2024). Uncommon presentation of transitional cell carcinoma: A case report of hand involvement. Clinical Case Reports, 12(9), e9358.https://doi.org/10.1002/ccr3.9358

 

Part 2 – You are only required to answer one case of your choosing.

 

Case 1: Review and interpret (i.e., explain) the endometrial biopsy reports:

 

  1. Report A: Atrophic endometrium.
  2. Report B: Atypical adenomatous hyperplasia.

 

Case 2: Two clients have persistent gastroesophageal reflux disease (GERD) despite therapy.  Review and interpret their biopsy reports:

 

  1. Report A: Low-grade dysplasia. This is an indication of early precancerous changes in the esophageal cells. Persistent GERD can result in Barret’s esophagus, increasing the risk of esophageal adenocarcinoma (Nieuwenburg et al., 2021).
  2. Report B: Intestinal metaplasia. This is a presentation of a more advanced stage in which the columnar epithelial goblet cells replace the squamous epithelial cells (Nieuwenburg et al., 2021). It is an indication of Barret’s esophagus symbolizing an adaptation to chronic acid exposure.

Add your Reference:

Nieuwenburg, S. A. V., Mommersteeg, M. C., Eikenboom, E. L., Yu, B., den Hollander, W. J., Holster, I. L., … & Spaander, M. C. (2021). Factors associated with the progression of gastric intestinal metaplasia: a multicenter, prospective cohort study. Endoscopy International Open, 9(03), E297-E305. doi: 10.1055/a-1314-6626.

 

Access the full solution for $10

Samson