NU621 Unit 2 Assignment: Anemia Classification
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SOLUTION NU621 Unit 2 Assignment: Anemia Classification
- Scenario 1-
-Thalassemia
-Microcytic hypochromic
-Pathophysiology: Thalassemia impaired synthesis of X or B-chain of hemoglobin A: Phagocytosis, Anemia with abnormal cell shapes or the presence of schistocytes, and formulate genetic defect of globin synthesis (Rogers, J., et al., 2025. P 918)
- Scenario 2
-Vitamin B12 Deficiency
-Macrocytic-normochromic
-Pathophysiology- The macrocytic (megaloblastic) anemias are characterized by large stem cells (megaloblasts) in the marrow (Fig. 29.4) that mature into erythrocytes that are unusually large in size (macrocytic; elevated MCV) thickness, and volume (see Fig. 29.3C). The most common etiology for macrocytic anemias is vitamin B12 or folate deficiencies. Vitamin B12 is dependent on dietary B12 intake. Plants and vegetables contain little cobalamin and strictly vegetarian and macrobiotic diets do not provide adequate amounts. Folate is found in green leafy vegetables, fruits, nuts, eggs, and meats……
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