Instructions

It is anticipated that the initial discussion post should be in the range of 250-300 words. Response posts to peers have no minimum word requirement but must demonstrate topic knowledge and scholarly engagement with peers. Substantive content is imperative for all posts. All discussion prompt elements for the topic must be addressed. Please proofread your response carefully for grammar and spelling. Do not upload any attachments unless specified in the instructions. All posts should be supported by a minimum of one scholarly resource, ideally within the last 5 years. Journals and websites must be cited appropriately. Citations and references must adhere to APA format.

Classroom Participation

Students are expected to address the initial discussion question by Wednesday of each week. Participation in the discussion forum requires a minimum of three (3) substantive postings (this includes your initial post and posting to two peers) on three (3) different days. Substantive means that you add something new to the discussion supported with citation(s) and reference(s), you are not just agreeing. This is also a time to ask questions or offer information surrounding the topic addressed by your peers. Personal experience is appropriate for a substantive discussion, however should be correlated to the literature.

All discussion boards will be evaluated utilizing rubric criterion inclusive of content, analysis, collaboration, writing and APA. If you fail to post an initial discussion or initial discussion is late, you will not receive points for content and analysis, you may however post to your peers for partial credit following the guidelines above.

Initial Response

Instructions:

Understanding the underlying pathophysiology of peripheral vascular disease is crucial for advanced practice nurses to effectively diagnose, manage, and educate patients on this condition.

In this week’s discussion, we will explore the pathophysiology of peripheral vascular disease (PVD). Please address the following in your post:

1. Describe the key pathophysiological mechanisms involved in the development of PVD.

1. • Consider the roles of atherosclerosis, endothelial dysfunction, and inflammation.

2. Identify the common risk factors that contribute to PVD.

1. • Discuss how modifiable (e.g., smoking, diabetes) and non-modifiable (e.g., age, genetics) risk factors influence disease progression.

3. Explain how PVD leads to the clinical manifestations seen in patients.

1. • Include symptoms such as intermittent claudication, rest pain, and critical limb ischemia.

4. Discuss the impact of PVD on systemic circulation and its potential complications.

1. • How does PVD relate to cardiovascular disease and increased risk for events such as myocardial infarction or stroke?

Responses need to address all components of the question, demonstrate critical thinking and analysis, and include peer reviewed journal evidence to support the student’s position.

Please be sure to validate your opinions and ideas with citations and references in APA format.

Please review the rubric to ensure that your response meets the criteria.

Your initial response is due by Wednesday at 11:59 pm CT.

Estimated time to complete: 2 hours

Peer Response

Instructions:

To ensure that your responses are substantive, consider one of the following prompts in your peer replies: 

• Regarding modifiable risk factors like smoking and diabetes in PVD, consider how lifestyle modifications or specific pharmacological interventions might alter the progression of PVD. How effective are these interventions in addressing the underlying pathophysiology versus managing the symptoms? 

• Expand on the discussion of how PVD contributes to systemic complications like myocardial infarction and stroke. How would you prioritize treatment strategies in a patient with both PVD and an increased risk of cardiovascular events? 

Responses need to address all components of the question, demonstrate critical thinking and analysis, and include peer reviewed journal evidence to support the student’s position.

Please be sure to validate your opinions and ideas with citations and references in APA format.

Please review the rubric to ensure that your response meets the criteria.

All peer responses are due by Sunday at 11:59 pm CT.

Estimated time to complete: 1 hour

SOLUTION NU621 Unit 2: Peripheral Vascular Disease

1.    Describe the key pathophysiological mechanisms involved in the development of PVD.
–    The pathophysiology behind PVD involves the narrowing by accumulation of lipids-laden macrophages within the arterial wall, which leads to the formation of lesions called plaque. The accumulation affects the vascular system throughout the body, leading to peripheral artery disease, CAD, and cerebrovascular disease (Rogers, J., 2023, p. 1069)
Consider the roles of atherosclerosis, endothelial dysfunction, and inflammation….

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